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Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
05/03/2024
St. Jude found 156 potential targets for chimeric antigen receptor (CAR) T–cell immunotherapy. Explore the discovery’s promise to improve cancer therapies.
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Unraveling the roles of non-coding DNA explains childhood cancer’s resistance to chemotherapy
05/01/2024
Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. Explore new technology used in the St. Jude-led discovery.
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Hongbo Chi, PhD named 2023 AAAS Fellow
04/29/2024
The St. Jude immunologist has made valuable contributions to immunometabolism. AAAS is the world’s largest general scientific society.
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Targeting specific protein regions offers a new treatment approach in medulloblastoma
04/25/2024
Explore how research targeting EP300/CBP protein in Group 3 medulloblastoma may advance targeted pediatric brain tumor treatments by inhibiting bromodomains.
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Genetics predict type 2 diabetes risk and disparities in childhood cancer survivors
04/23/2024
Learn how ancestry changes genetic risk variants’ impact on type 2 diabetes in childhood cancer survivors & alkylating agent exposure magnifies diabetes risk.
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Metabolic health before vaccination determines effectiveness of anti-flu response
04/18/2024
Poor metabolic health or dysfunction, not obesity, leads to poor anti-influenza immune responses. Learn about the new St. Jude influenza vaccination research.
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Andrew Smith, MD, PhD, named chair of Diagnostic Imaging at St. Jude Children’s Research Hospital
04/15/2024
Andrew Smith, MD, PhD, named chair of Diagnostic Imaging at St. Jude Children's Research Hospital. Smith is an expert in the use of artificial intelligence in imaging and medicine.
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New drug prevents flu-related inflammation and lung damage
04/10/2024
New RIPK3 inhibitor UH15-38 protected models against influenza-induced inflammation and lung injury. Learn how it selectively blocks pathogenic necroptosis.
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St. Jude survivorship portal brings researchers ‘one-click’ away from discovery
04/09/2024
Learn about the survivorship portal, a part of the St. Jude Cloud ecosystem, and find out how researchers can use the portal to make new discoveries.
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Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
04/08/2024
Discover how a vulnerability in treatment resistant B-cell acute lymphoblastic leukemia (B-ALL) was uncovered by single-cell analysis of developmental stage.
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Scientific Report 2023
The Scientific Report, Translating Science into Survival, describes key breakthroughs made by St. Jude investigators.
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